Modern Care Journal

Published by: Kowsar

The Effects of Grape Seed Extract Ointment on Approximation of Cesarean Section Wound

Sima Soorgi 1 , Ali Mohammad Izadpanah 2 , * , Gholam Reza Sharifzadeh 3 , Marziyeh Torshizi 2 , Zohreh Khazaye 4 and Mohammad Hasanpour 5
Authors Information
1 Faculty of Nursing and Midwifery, Birjand University of Medical Sciences, Birjand, IR Iran
2 East Nursing and Midwifery Research Center, Birjand University of Medical Sciences, Birjand, IR Iran
3 Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, IR Iran
4 Department of Gynecology, Faculty of Medicine, Birjand University of Medical Sciences. Birjand, IR Iran
5 Department of Physiology and Pharmacology, Faculty of Medicine, Birjand University of Medical Science, Birjand, IR Iran
Article information
  • Modern Care Journal: January 2016, 13 (1); e8849
  • Published Online: January 30, 2016
  • Article Type: Research Article
  • Received: August 5, 2015
  • Revised: December 6, 2015
  • Accepted: December 23, 2015
  • DOI: 10.17795/modernc.8849

To Cite: Soorgi S, Izadpanah A M, Sharifzadeh G R, Torshizi M, Khazaye Z, et al. The Effects of Grape Seed Extract Ointment on Approximation of Cesarean Section Wound, Mod Care J. 2016 ; 13(1):e8849. doi: 10.17795/modernc.8849.

Copyright © 2016, Birjand University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. James D, Philip J, Steer P, Weiner C, Gonik B. High risk pregnancy. 1999;
  • 2. Rahmanian K, Ghasvari M, Rahmanian V. Cesarean, ever to need attention: prevalence and causes of cesarean section in Jahrom, 1387. J Jahrom Univ Med Sci. 2011; 9(1): 46-54
  • 3. Jouhari SH, Bayati S, Kheirabadi A, Poor F, Moradi E. Cesarean Section Rate and Its Cause in Fasa in the Year 2011. Journal of Fasa University of Med Sci. 2014; 4(3): 295-300
  • 4. Wilson JA, Clark JJ. Obesity: impediment to postsurgical wound healing. Adv Skin Wound Care. 2004; 17(8): 426-35[PubMed]
  • 5. Schneid-Kofman N, Sheiner E, Levy A, Holcberg G. Risk factors for wound infection following cesarean deliveries. Int J Gynaecol Obstet. 2005; 90(1): 10-5[DOI][PubMed]
  • 6. Koigi-Kamau R, Kabare LW, Wanyoike-Gichuhi J. Incidence of wound infection after caesarean delivery in a district hospital in central Kenya. East Afr Med J. 2005; 82(7): 357-61[PubMed]
  • 7. De Vivo A, Mancuso A, Giacobbe A, Priolo AM, De Dominici R, Maggio Savasta L. Wound length and corticosteroid administration as risk factors for surgical-site complications following cesarean section. Acta Obstet Gynecol Scand. 2010; 89(3): 355-9[DOI][PubMed]
  • 8. Heidari T, Roozbahani N, Farahani L, Attarha M, Torkestani N, Jamilian M, et al. Does Iranian Astragalus gossypinus honey assist in healing caesarean wounds and scars? Eur J Integrat Med. 2013; 5(3): 226-33
  • 9. Veisi F, Zangeneh M, Malekkhosravi S, Rezavand N, Hemiari K, Rezaei M. Subcutaneous vicryl suture covering efficacy on wound complications after cesarean section. J Kermanshah Univ Med Sci. 2011; 15(3)
  • 10. Moslemi HR, Jamshidi K, Tavangar MM, Kafshdouzan K. Study of the Effects of Urtica dioica Ointment on the Coetaneous Wound Healing in Cattle. J Med Plants. 2012; 2(42): 177-82
  • 11. Hsu S. Green tea and the skin. J Am Acad Dermatol. 2005; 52(6): 1049-59[DOI][PubMed]
  • 12. Kahkonen MP, Hopia AI, Vuorela HJ, Rauha JP, Pihlaja K, Kujala TS, et al. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem. 1999; 47(10): 3954-62[PubMed]
  • 13. Salari A, Habibi-Najafi MB, Farhoosh R, Marashi SH. Grape (Vitis vinifera) seed extraction with different solvent systems and assay of antioxidant and antiradical properties. Iran Food Sci Technol Res J. 2009; 5(1): 1-10
  • 14. Montaseri M, Ezadi Z, Ezadi M, Sohrabi M. Examine some quality characteristics of grape seed oil and its effects on human health. The second national Conference on Functional Food (Amalgar). 2008;
  • 15. Khanna S, Venojarvi M, Roy S, Sharma N, Trikha P, Bagchi D, et al. Dermal wound healing properties of redox-active grape seed proanthocyanidins. Free Radic Biol Med. 2002; 33(8): 1089-96[PubMed]
  • 16. Hojati , Kazemi K, Tanideh N, Syvani E, Roushan N. The effect of egg yolk and gum tragacunt ointment on wound healing: An experimental study on rabbits. J Med Res. 2004; 2(2): 33-8
  • 17. Magann EF, Chauhan SP, Rodts-Palenik S, Bufkin L, Martin JJ, Morrison JC. Subcutaneous stitch closure versus subcutaneous drain to prevent wound disruption after cesarean delivery: a randomized clinical trial. Am J Obstet Gynecol. 2002; 186(6): 1119-23[PubMed]
  • 18. Sehhati Shaffaie F, Rashidi Fakari F, Javadzadeh Y, Ghojazadeh M. Effect of the phenytoin cream on episiotomy healing in primipara women. SSU J. 2012; 20(2): 152-8
  • 19. Hemmati AA, Foroozan M, Houshmand G, Moosavi ZB, Bahadoram M, Maram NS. The topical effect of grape seed extract 2% cream on surgery wound healing. Glob J Health Sci. 2015; 7(3): 52-8[DOI][PubMed]
  • 20. Hemmati AA, Aghel N, Rashidi I, Gholampur-Aghdami A. Topical grape (Vitis vinifera) seed extract promotes repair of full thickness wound in rabbit. Int Wound J. 2011; 8(5): 514-20[DOI][PubMed]
  • 21. Nayak BS, Ramdath DD, Marshall JR, Isitor GN, Eversley M, Xue S, et al. Wound-healing activity of the skin of the common grape (Vitis Vinifera) variant, Cabernet Sauvignon. Phytother Res. 2010; 24(8): 1151-7[DOI][PubMed]
  • 22. Khanna S, Roy S, Bagchi D, Bagchi M, Sen CK. Upregulation of oxidant-induced VEGF expression in cultured keratinocytes by a grape seed proanthocyanidin extract. Free Radic Biol Med. 2001; 31(1): 38-42[PubMed]
  • 23. Bastami A, Davari Dehkordi N, Ziagham S. The Effect of phonation cream on cesarean wound healing. Iran J Obstet Gynecol Infertil. 2014; 17(103): 14-20
  • 24. Saedi Z, Behbahan M. Evaluation of methanol extracts activity of seed, skin, leaf and juice from five Iranian grape cultivars on lymphocyte proliferation. J Res Med. 2014; 37(4): 200-4
  • 25. Golmakani N, Rabiei ME, Tara F, Asili J, Shakeri MT. The effects of turmeric (Curcuma longa L) ointment on healing of episiotomy site in primiparous women. Iran J Obstetr Gynecol Infertil. 2009; 11(4): 29-39
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments