Modern Care Journal

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The Prevalence of Major Congenital Anomalies Among Live Births in Birjand, Iran

Gholamreza Faal 1 , * , Razieh Abbasi 1 and Bita Bijari 1
Authors Information
1 Pediateric Ward, University of Medical Sciences, Birjand, IR Iran
Article information
  • Modern Care Journal: April 2018, 15 (2); e81084
  • Published Online: April 28, 2018
  • Article Type: Research Article
  • Received: December 20, 2017
  • Revised: March 22, 2018
  • Accepted: April 15, 2018
  • DOI: 10.5812/modernc.81084

To Cite: Faal G, Abbasi R, Bijari B. The Prevalence of Major Congenital Anomalies Among Live Births in Birjand, Iran, Mod Care J. 2018 ; 15(2):e81084. doi: 10.5812/modernc.81084.

Copyright © 2018, Modern Care Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Hematyar M, Khajouie P. Prevalence of congenital anomalies in 1000 live births in Javaheri Hospital, Tehran, 2004. Med Sci J Islamic Azad Univ. 2005;15(2):75-8.
  • 2. Mohammadzadeh I, Sorkhi H, Alizadeh-Navaei R. Prevalence of external congenital malformations in neonates born in Mehregan Hospital, North of Iran. Gene 3rd Millennium. 2013;11(1):2990-5.
  • 3. Uptodate . Approach to congenital malformations. 2016. Available from:
  • 4. Mohsenzadeh A, Saket S, Ahmadipour S, Baharvand B. Prevalence and types of congenital heart disease in babies born in the city of Khorramabad (2007- 2011). Yafte. 2014;15(5):23-9.
  • 5. Sarkar S, Patra C, Dasgupta MK, Nayek K, Karmakar PR. Prevalence of congenital anomalies in neonates and associated risk factors in a tertiary care hospital in eastern India. J Clin Neonatol. 2013;2(3):131-4. doi: 10.4103/2249-4847.119998. [PubMed: 24251257]. [PubMed Central: PMC3830148].
  • 6. Khatami F, Mamuri G. Survey of congenital major malformation in 10,000 newborns. Iran J Pediatr. 2005;15(4):315-20.
  • 7. Dastgiri S, Mizani T, Bonyadi M. The prevalence of genetic disorders in East Azerbaijan province. J Urmia Univ Med Sci. 2010;21(4):339-46.
  • 8. Sokal R, Tata LJ, Fleming KM. Sex prevalence of major congenital anomalies in the United Kingdom: a national population-based study and international comparison meta-analysis. Birth Defects Res A Clin Mol Teratol. 2014;100(2):79-91. doi: 10.1002/bdra.23218. [PubMed: 24523198]. [PubMed Central: PMC4016755].
  • 9. Golalipour MJ, Vakili MA. Gross congenital malformations in 10000 births (Gorgan Dezyani Hospital 1997-99). J Gorgan Univ Med Sci. 2002;4(2):42-7.
  • 10. Alijahan R, Mirzarahimi M, Ahmadi Hadi P, Hazrati S. Prevalence of Congenital Abnormalities and Its Related Risk Factors in Ardabil, Iran, 2011. Iran J Obstetr Gynecol Infertil. 2013;16(54):16-25.
  • 11. Sallout BI, Al-Hoshan MS, Attyyaa RA, Al Suleimat AA. Antenatal diagnosis, prevalence and outcome of major congenital anomalies in Saudi Arabia: a hospital-based study. Ann Saudi Med. 2008;28(4):272-6. [PubMed: 18596401].
  • 12. Yu JR, Jin L, Xiao LH, Jin L. [Prevalence of birth defects in the Tongzhou District of Beijing between 2006 and 2012]. Zhongguo Dang Dai Er Ke Za Zhi. 2014;16(11):1133-7. Chinese. [PubMed: 25406559].
  • 13. Yang M, Zhang S, Du Y. Epidemiology characteristics of birth defects in Shenzhen city during 2003 to 2009, China. J Matern Fetal Neonatal Med. 2015;28(7):799-803. doi: 10.3109/14767058.2014.932767. [PubMed: 24974918].
  • 14. Chen BY, Hwang BF, Guo YL. Epidemiology of congenital anomalies in a population-based birth registry in Taiwan, 2002. J Formos Med Assoc. 2009;108(6):460-8. doi: 10.1016/S0929-6646(09)60093-0. [PubMed: 19515626].
  • 15. Kim MA, Yee NH, Choi JS, Choi JY, Seo K. Prevalence of birth defects in Korean livebirths, 2005-2006. J Korean Med Sci. 2012;27(10):1233-40. doi: 10.3346/jkms.2012.27.10.1233. [PubMed: 23091323]. [PubMed Central: PMC3468762].
  • 16. Pangkanon S, Sawasdivorn S, Kuptanon C, Chotigeat U, Vandepitte W. Establishing of National Birth Defects Registry in Thailand. J Med Assoc Thai. 2014;97 Suppl 6:S182-8. [PubMed: 25391192].
  • 17. Tomatir AG, Demirhan H, Sorkun HC, Koksal A, Ozerdem F, Cilengir N. Major congenital anomalies: a five-year retrospective regional study in Turkey. Genet Mol Res. 2009;8(1):19-27. [PubMed: 19224463].
  • 18. Singh R, al-Sudani O. Major congenital anomalies at birth in Benghazi, Libyan Arab Jamahiriya, 1995. East Mediterr Health J. 2000;6(1):65-75. [PubMed: 11370343].
  • 19. Dolk H, Loane M, Garne E. The prevalence of congenital anomalies in Europe. Adv Exp Med Biol. 2010;686:349-64. doi: 10.1007/978-90-481-9485-8_20. [PubMed: 20824455].
  • 20. Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, et al. Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol. 2010;88(12):1008-16. doi: 10.1002/bdra.20735. [PubMed: 20878909].
  • 21. Kavianyn N, Mirfazeli A, Aryaie M, Hosseinpour K, Golalipour MJ. Incidence of birth defects in Golestan province. J Gorgan Univ Med Sci. 2016;17(4).
  • 22. Hosseini S, Nikravesh A, Hashemi ZS, Rakhshi N. Race of apparent abnormalities in neonates born in Amir-Almomenin hospital of Sistan. J North Khorasan Univ Med Sci. 2014;6(3):573-9. doi: 10.29252/jnkums.6.3.573.
  • 23. Amini Nasab Z, Aminshokravi F, Moodi M, Eghbali B, Fatemimogadam F. Demographical condition of neonates with congenital abnormalities under Birjand city health centers during 2007-2012. J Birjand Univ Med Sci. 2014;21(1):96-103.
  • 24. Cambra K, Ibanez B, Urzelai D, Portillo I, Montoya I, Esnaola S, et al. Trends in the prevalences of congenital anomalies and age at motherhood in a southern European region: a population-based study. BMJ. 2014;4(3). e004244.
  • 25. Ciancimino L, Laganà AS, Chiofalo B, Granese R, Grasso R, Triolo O. Would it be too late? A retrospective case–control analysis to evaluate maternal–fetal outcomes in advanced maternal age. Arch Gynecol Obstetr. 2014;290(6):1109-14. doi: 10.1007/s00404-014-3367-5.
  • 26. Kirby RS, Marshall J, Tanner JP, Salemi JL, Feldkamp ML, Marengo L, et al. Prevalence and correlates of gastroschisis in 15 states, 1995 to 2005. Obstet Gynecol. 2013;122(2 Pt 1):275-81. doi: 10.1097/AOG.0b013e31829cbbb4. [PubMed: 23969795]. [PubMed Central: PMC4605404].
  • 27. Malik S, Cleves MA, Honein MA, Romitti PA, Botto LD, Yang S, et al. Maternal smoking and congenital heart defects. Pediatrics. 2008;121(4):e810-6. doi: 10.1542/peds.2007-1519. [PubMed: 18381510].
  • 28. Sallout B, Obedat N, Shakeel F, Mansoor A, Walker M, Al-Badr A. Prevalence of major congenital anomalies at King Fahad Medical City in Saudi Arabia: a tertiary care centre-based study. Ann Saudi Med. 2015;35(5):343-51. doi: 10.5144/0256-4947.2015.343. [PubMed: 26506967].
  • 29. Dursun A, Zenciroglu A, Hakan N, Karadag N, Karagol BS, Aydin B, et al. Distribution of congenital anomalies in a neonatal intensive care unit in Turkey. J Matern Fetal Neonatal Med. 2014;27(10):1069-74. doi: 10.3109/14767058.2013.847420. [PubMed: 24059457].
  • 30. Sereshti M, Banaeyan S, Kazemeyan A. Prevalence of apparent major congenital malformations and some associated factors, in terminated pregnancies in hajar hospital of shahrekord, 2005-2006, iran. J Shahrekord Univ Med Sci. 2008;10(1).
  • 31. Marzban A, Sadeghizadeh M, Mosavinasab SN. Incidence of Gross congenital neural tube defect and its risk factors in new borns at obstetric centre of Vally-e-Asr Hospital in Zanjan. J Mazandaran Univ Med Sci. 2005;15(46):82-6.
  • 32. Golalipour MJ, Vakili MA. Neural tube defects in newborns and relation with consanguineous marriage, ethnicity and mother’s age in Gorgan. J Gorgan Univ Med Sci. 2003;5(2):30-5.
  • 33. Singh A, Gupta RK. Pattern of congenital anomalies in newborn: A hospital based prospective study. JK Sci. 2009;11:34-6.
  • 34. Hagberg C, Larson O, Milerad J. Incidence of cleft lip and palate and risks of additional malformations. Cleft Palate Craniofac J. 1998;35(1):40-5. doi: 10.1597/1545-1569_1998_035_0040_ioclap_2.3.co_2. [PubMed: 9482222].
  • 35. Shawky RM, Sadik DI. Congenital malformations prevalent among Egyptian children and associated risk factors. Egypt J Med Human Gene. 2011;12(1):69-78. doi: 10.1016/j.ejmhg.2011.02.016.
  • 36. Hamdan MA, Chedid F, Bekdache GN, Begam M, Alsafi W, Sabri Z, et al. Perinatal outcome of congenital heart disease in a population with high consanguinity. J Perinatal Med. 2015;43(6). doi: 10.1515/jpm-2014-0019.
  • 37. El Koumi MA, Al Banna EA, Lebda I. Pattern of congenital anomalies in newborn: a hospital-based study. Pediatr Rep. 2013;5(1). e5. doi: 10.4081/pr.2013.e5. [PubMed: 23667734]. [PubMed Central: PMC3649744].
  • 38. Leonardi-Bee J, Britton J, Venn A. Secondhand smoke and adverse fetal outcomes in nonsmoking pregnant women: a meta-analysis. Pediatrics. 2011;127(4):734-41. doi: 10.1542/peds.2010-3041. [PubMed: 21382949].
  • 39. Louanne H, Suzanne B. Cassidy congenital anomalies. In: Fanaroff M, editor. Neonatal Perinatal Medicine. Philadelphia: Mosby; 2006. p. 561-82.
  • 40. Amini A, Zamani A. Prevalence of congenital anomalies in newborns. IJFM. 2000;20(1):19-25.
  • 41. Madi SA, Al-Naggar RL, Al-Awadi SA, Bastaki LA. Profile of major congenital malformations in neonates in Al-Jahra region of Kuwait. East Mediterr Health J. 2005;11(4):700-6. [PubMed: 16700386].
  • 42. Lary JM, Paulozzi LJ. Sex differences in the prevalence of human birth defects: a population-based study. Teratology. 2001;64(5):237-51. doi: 10.1002/tera.1070. [PubMed: 11745830].
  • 43. Garne E, Hansen AV, Birkelund AS, Andersen AM. Major congenital anomalies in a Danish region. Dan Med J. 2014;61(6). A4825. [PubMed: 24947618].

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